This is how antibiotic resistance spreads in bacterial populations – healing practice

This is how antibiotic-resistant genes spread between bacteria

Now, for the first time, the Structure of the transport apparatus shown, the the Allows spread of antibiotic-resistant genes between bacteria. A better understanding of how these antibiotic-resistant genes spread could help to stop or at least curb the spread of antibiotic-resistant microorganisms in the future.

In a new study involving experts from University College London (UCL) was analyzed as the so-called bacterial conjugation enables unidirectional transfer of DNA from a donor cell to a recipient cell. This is the main way through Spreading antibiotic resistance genes in bacterial populations.

The corresponding study results were published in the English-language journal “Nature“ published.

Why antibiotic resistance is increasing

The researchers emphasize that increasing antibiotic resistance poses a serious threat to all of humanity. Antibiotic resistance is a naturally occurring phenomenon, but it is caused by the excessive and incorrect use of antibiotics amplified in humans and animals.

According to the experts at Robert Koch Institute (RKI) encourages every single use of antibiotics the formation of resistance. This is because non-resistant bacteria do not survive such treatment, while resistant bacteria survive and spread continue to multiply.

Therefore, it is logical that antibiotic-resistant pathogens often occur where particularly lots of antibiotics are usedsuch as in hospitals and agriculture.

Problems in the treatment of infectious diseases

The rise of antibiotic-resistant bacteria threatens the Treatment options for many infectious diseases, according to the researchers involved in the current study. The RKI also emphasizes that infections with resistant pathogens usually spread more difficult to treat and one take a more complicated course be able.

We are in a global antimicrobial resistance crisis that threatens to devastate health systems around the world – the World Health Organization identifies antimicrobial resistance as one of the greatest threats to global health, food safety and development today‘ explains the author of the study Professor Gabriel Waksman in a current press release.

Although the emergence of antibiotic resistance cannot be prevented, an understanding of exactly how bacteria are able to exchange genes could open up approaches to prevent them Combating the spread of antibiotic-resistant genes.

The current research work is making a decisive contribution here and using cryo-electron microscopy is showing how precisely the Antibiotic resistance spreads in bacterial populations. An extraordinarily large protein-protein interaction network plays an essential role here. (as)

Author and source information

This text corresponds to the specifications of medical specialist literature, medical guidelines and current studies and has been checked by medical professionals.


  • Abhinav K. Vadakkepat, Adam Redzej, Natalya Lukoyanova, Clasien Oomen, Nathalie Braun, et al.: Cryo-EM structure of a type IV secretion system; in: Nature (published 06/22/2022), Nature
  • University College London: New hope to stop spread of antibiotic resistance (published 23.06.2022), UCL
  • Robert Koch Institute: Basic knowledge of antibiotic resistance (as of May 9th, 2019), RKI

Important NOTE:
This article contains general advice only and should not be used for self-diagnosis or treatment. He can not substitute a visit at the doctor.

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