Nasal spray against Alzheimer’s: drug is being tested on humans for the first time

  • Drug Study: Is there a breakthrough in Alzheimer’s research soon?
  • Nasal spray in test phase: 16 study participants will check the compatibility
  • Confident researchers: Drug could slow down or even prevent Alzheimer’s disease
  • This is how the study will go

Memory loss, confusion and disorientation: dementia is a slowly progressing one Brain disease, makes life difficult for those affected and their loved ones. The disease causes suffering for everyone involved. Most of the sick are from Alzheimer affected – a form of dementia. After 20 years of research, a clinical trial is now beginning in the USA to test the safety and effectiveness of a new vaccine against the disease administered through the nose. He should Slowing down or even preventing the progression of Alzheimer’s disease.

Every year around 300,000 people in Germany develop dementia – most of them from Alzheimer’s

Details of the German Alzheimer’s Society according to each year around 300,000 people Germany-wide at the Dementia. Depending on the further development of the population, between 2.4 and 2.8 million people could live in Germany by 2050 Alzheimer suffer – at least if no real progress remains in research for treatment.

A team of researchers is now expecting precisely this progress from a nasal spray that was carried out as part of a first series of human experiments 16 people in the US should be tested. The study participants are between 60 and 85 years old and show all first Alzheimer’s symptoms.

In the clinical study, the 16 participants received via the nose two doses of vaccine at an interval of one week. The main objective of the phase I study is to demonstrate the safety and tolerability of the vaccine. The research team will also measure the effect of Protollin on the participants’ immune response.

The first test phase is intended to confirm the safety of the drug

At a Alzheimer’s diseaseg arise beta-amyloid proteins, which are known as Alzheimer’s plaque are deposited between the nerve cells and cannot be broken down by the body. According to the researchers, the nasal spray called Protollin used in the series of experiments will help to dissolve this Alzheimer’s plaque.

The test should first prove that the nasal spray is safe and well tolerated by the patient. In addition, the effect of the Nasal sprays on the immune system and examined the white blood cells. The researchers have great hopes for the new drug. Many sick people and their relatives could thus be relieved of a huge burden in the future and quality of life restored.

You might also be interested in: Recognizing Alzheimer’s and dementia early: this is what your eyes play.

source site