The drug xylazine designated “emerging threat”, a first

The United States faces a new drug epidemic. The country announced on Wednesday designating xylazine, nicknamed “tranq”, as an “emerging threat”, in particular in order to be able to release funds to fight against this drug which is already wreaking havoc in the country. “This is the first time in our nation’s history that a substance has been designated as an emerging threat,” Dr. Rahul Gupta, director of the drug enforcement office at the United Nations, told a news conference. White House.

Xylazine, licensed as a veterinary sedative and analgesic since 1972 by the US Drug Administration (FDA), is not approved outside of animal use. In humans, its consumption can slow breathing and heart rate to dangerous levels, and cause infections that can lead to limb amputations. Between 2020 and 2021, detection of xylazine by the United States Drug Enforcement Agency (DEA) increased by almost 200% in the south of the country, and more than 100% in the west.

“America’s Problem”

The designation as an emerging threat must allow the use of funds requested by President Joe Biden from the United States Congress in his 2024 budget, explained Rahul Gupta. “We need the support of Congress,” he pleaded, so as not to have to redirect money dedicated to other causes. “It is not a problem concerning the States” democrats or republicans, “it is the problem of America”, he hammered.

The government is required, within three months of designation, to present an action plan to Congress, which will address several areas. Among them: more tests to detect the drug and analyzes to better understand where it comes from – especially if it is diverted in the United States or from China – in order to better fight against its growing presence on the illegal market. . Another priority is medical research.

Need an antidote

“We will bring together national experts in the field to guide practice, and identify the most promising approaches for clinical stabilization, withdrawal management, and treatment protocols,” detailed Rahul Gupta. Moreover, “we need an antidote”, which does not exist to date, he added.

Naloxone, an antidote that can resuscitate a person in the process of overdosing on an opioid (eg fentanyl), is not effective against xylazine. Fentanyl and xylazine, both synthetic, are often found together in the same product, according to the DEA. In February, the American health authorities had launched an “import alert” in order to better control the deliveries of xylazine, to ensure that they are indeed intended for veterinary use.

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