Study shows new risk factor for dementia – herpes infection has an enormous impact

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About two thirds of the world’s population is infected with herpes. According to a new study, this significantly increases the risk of developing dementia.

Uppsala – Dementia is still an incurable disease that affects over a million people in Germany alone. A lot of research is being carried out to identify additional risk factors, improve early detection and possibly develop an effective treatment in the future. A team of scientists from Uppsala University has now developed a study Another risk factor was detected: an infection with the herpes simplex virus (HSV). The study participants who carried the virus were significantly more likely to develop dementia than those who were not infected.

Does herpes increase the risk of developing dementia? A study says yes – and to a significant extent. © Batuhan Toker/IMAGO

In the study, people infected with herpes had a significantly increased risk of developing dementia

As early as November 2023, a research team from Columbia University presented one study, which suggested a connection between herpes and dementia. This theory has now been further supported by the Swedish study. Study participants who were infected with HSV had twice the risk of developing dementia.

Erika Vestin, the lead author of the study, emphasized in a Press release from Uppsala University: “The special thing about this study is that the participants are approximately the same age, which makes the results even more reliable, as age differences, which are otherwise associated with the development of dementia, cannot distort the results.” She also sees the results as an opportunity for further research into potential cures.

The herpes simplex virus

There are a total of over 200 herpes viruses, nine of which are specific to humans. The herpes simplex virus (HSV) is probably the best known of them. It occurs in two different types: Type 1 and Type 2.

HSV type 1 (HSV-1) primarily presents itself as Cold sores noticeable. It is transmitted primarily through saliva.
HSV type 2 (HSV-2) is mostly transmitted through sexual contact and is the most common cause of Genital herpes.

In principle, however, both types can cause both cold and genital herpes. There is neither an effective vaccine nor a drug to combat HSV. Once infected, you carry the virus for life.

Source: Helmholtz Center for Infection Research

Further research into herpes as a dementia risk factor is needed

Vestin added: “The findings could further advance dementia research to treat the disease at an early stage with common anti-herpes virus drugs or to prevent the disease before it occurs.” However, she also stressed that further research is needed to unequivocally confirm that HSV infection is a risk factor for dementia.

There are also things that everyone can do to prevent dementia. Women in particular should take good preventive measures because they are more likely to develop dementia as they get older than men. (sp)

The editor wrote this article and then used an AI language model for optimization at his own discretion. All information has been carefully checked. Find out more about our AI principles here.

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