Many people find it unpleasant when a grape seed gets stuck between their teeth. Aside from having no particular taste, grape seeds taste bitter to most people. For this reason, seedless grape varieties are very popular. Although seedless varieties also occur in nature, these berries are usually very small.
In order to obtain seedless grapes with good taste, they are selectively bred and manipulated with hormones during growth. Specifically, this means: The grape vines are sprayed with gibberellins and auxin during the growth phase. As a result, the fruits do not form seeds, are further apart and are larger when harvested than untreated fruits.
While the end result is considered safe for human consumption, there is a lack of research into possible long-term effects. But simply avoiding grape seeds is not necessarily good for your health.