Carla Gugino, Lucy Liu and Paul Giamatti were among the celebrities taking a stand as they hit the picket line in New York on Monday.
The actors are in their third week of protests for better wages and protections from the major Hollywood studios.
Carla, 51, looked comfortable in a black V-neck top and red jeans.
The Leopard Skin star styled her dark, curly hair into a high ponytail and wore large aviator glasses as she joined her fellow strikers